Cross-matching is one of the test performed prior to blood transfusion to minimize transfusion reaction. Major cross-match and minor cross-match are usually performed.🩸
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-Major cross-match = Mixing a drop of donor red blood cells and patient plasma/serum
-Minor cross-match = Mixing a drop of donor plasma/serum and patient red blood cells
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If the blood product isn’t compatible then autoagglutination might occur (see pic abnormal)